John A Zebala Selected Research

Aminopterin

1/2014	LD-aminopterin in the canine homologue of human atopic dermatitis: a randomized, controlled trial reveals dosing factors affecting optimal therapy.
9/2012	Intestinal transport of aminopterin enantiomers in dogs and humans with psoriasis is stereoselective: evidence for a mechanism involving the proton-coupled folate transporter.
6/2008	Phase 2B trial of aminopterin in multiagent therapy for children with newly diagnosed acute lymphoblastic leukemia.
12/2007	High-performance liquid chromatography separation of aminopterin-polyglutamates within red blood cells of children treated for acute lymphoblastic leukemia.

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John A Zebala Research Topics

Disease

7	Neoplasms (Cancer) 01/2022 - 09/2015
2	Prostatic Neoplasms (Prostate Cancer) 01/2017 - 01/2017
2	Inflammation (Inflammations) 06/2015 - 10/2014
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 06/2008 - 12/2007
1	Carcinoma (Carcinomatosis) 02/2021
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Squamous Cell Carcinoma of Head and Neck 01/2020
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2019
1	Pain (Aches) 01/2019
1	Colorectal Neoplasms (Colorectal Cancer) 01/2019
1	Respiratory Insufficiency (Respiratory Failure) 01/2019
1	Neoplasm Metastasis (Metastasis) 01/2017
1	Pneumonia (Pneumonitis) 06/2015
1	Carcinogenesis 10/2014
1	Atopic Dermatitis (Atopic Eczema) 01/2014
1	Psoriasis (Pustulosis Palmaris et Plantaris) 09/2012
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2010
1	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Leukemia, Pre B Cell) 06/2008

Drug/Important Bio-Agent (IBA)

4	Immune Checkpoint InhibitorsIBA 02/2021 - 01/2017
4	AminopterinIBA 01/2014 - 12/2007
3	Chemokine ReceptorsIBA 09/2015 - 01/2010
2	GTP-Binding Proteins (G-Protein)IBA 01/2019 - 10/2014
2	Pharmaceutical PreparationsIBA 09/2015 - 06/2015
1	LigandsIBA 01/2022
1	Interleukin-15 (Interleukin 15)IBA 02/2021
1	Cancer VaccinesIBA 02/2021
1	VaccinesIBA 02/2021
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 02/2021
1	AntigensIBA 02/2021
1	Phenobarbital (Luminal)FDA Link 01/2021
1	Interleukin-17 (Interleukin 17)IBA 01/2021
1	Interleukin-8 (Interleukin 8)IBA 01/2020
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2020
1	Cadherins (E-Cadherin)IBA 01/2020
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020
1	Oxycodone (Oxycontin)FDA LinkGeneric 01/2019
1	Opioid Receptors (Opioid Receptor)IBA 01/2019
1	Opioid Analgesics (Opioids)IBA 01/2019
1	Morphine (MS Contin)FDA LinkGeneric 01/2019
1	Fentanyl (Sublimaze)FDA LinkGeneric 01/2019
1	Prostate-Specific Antigen (Semenogelase)IBA 01/2017
1	AndrogensIBA 01/2017
1	AntibodiesIBA 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	CytokinesIBA 01/2017
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2017
1	B7-H1 AntigenIBA 01/2017
1	2- (5- (4- fluorophenylcarbamoyl)pyridin- 2- ylsulfanylmethyl)phenylboronic acidIBA 10/2014
1	ChemokinesIBA 10/2014
1	Proton-Coupled Folate TransporterIBA 09/2012

Therapy/Procedure

8	Therapeutics 02/2021 - 06/2008
4	Immunotherapy 02/2021 - 01/2017
2	Castration 01/2017 - 01/2017